// peer-reviewed · 6 papers
Nature Biotechnology · 43, 1911–1918 · Contributing author
Fifteen years of writing yeast chromosomes from scratch and what we learnt about debugging an engineered genome. Tells the consortium story of how SCRaMbLE, neochromosome rescue, and parallel debugging changed how we think about programmable life.
Nature Communications · Co-author
Built chromosome XVI from scratch, watched it fail, then redesigned it. Reports the rational debugging loop — phenotype, mutation map, targeted fix — that turned a sick chromosome into a working one.
Bioinformatics Advances · First author
An open-source tool that turns plate-reader CSV exports into publication-ready growth curves in under a minute. Solves the daily pain of every lab doing 96/384-well kinetics. Live at synbioexplorer.pythonanywhere.com.
ACS Synthetic Biology · First author
NLP analysis of 23,000+ syn-bio papers to map how the field is actually moving — what topics rise, which institutions cluster, where the funding goes. A landscape view of a discipline by reading everything it has ever published.
Nature Communications · Co-author
Review of strategies for genome minimisation — cutting organisms down to their essential gene set, then re-adding only what new function you want. The argument that "less is more" can be engineered.
Cell Genomics · Co-author
When a synthetic chromosome breaks the cell, you can either re-engineer it or let evolution find its own fix. This paper does both in parallel and shows yeast adapts faster than humans can engineer.
// in the pipeline · 3 manuscripts
Nucleic Acids Research
Essential neochromosome for SCRaMbLE viability — making synthetic chromosomes that survive their own evolution.
TBD
Oscillating selection in yeast adaptive laboratory evolution. Time-modulated selection pressure changes what evolution finds.
FEMS Yeast Research
Nanopore pipeline for synthetic cassette mapping — sequencing-based QC for designer DNA constructs.
// coesb · network of experts
Interactive visualisation I built for the ARC Centre of Excellence in Synthetic Biology (COESB): every node is a researcher, every link is a co-authored paper.
The network captures collaborative relationships between COESB members and their external collaborators since the Centre's establishment. Only papers reported to the Centre are included.
Built the pipeline end-to-end: DOI list → Crossref API → author parsing → NetworkX graph → vis-network interactive viz. Captures 7,600+ co-author links across hundreds of researchers.
loading 1,161 nodes · 7,648 edges
COESB · co-authorship
click a node → highlight neighbours
— researchers
— co-author links
native render · ~1.5 MB data + 470 KB vis-network · zero external runtime dependencies · loads when scrolled into view